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2 edition of Bioassay of tetrachloroethylene for possible carcinogenicity. found in the catalog.

Bioassay of tetrachloroethylene for possible carcinogenicity.

National Institute of Health (U.S.). Carcinogen Bioassay and Program Resources Branch.

Bioassay of tetrachloroethylene for possible carcinogenicity.

by National Institute of Health (U.S.). Carcinogen Bioassay and Program Resources Branch.

  • 328 Want to read
  • 10 Currently reading

Published by [Dept. of Health, Education, and Welfare, Public Health Service], National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Program, Carcinogen Bioassay and Program Resources Branch in Bethesda, Md .
Written in English

    Subjects:
  • Tetrachloroethylene -- Physiological effect.,
  • Carcinogens.

  • Edition Notes

    SeriesDHEW publication ; no. (NIH) 77-813, Carcinogenesis technical report series ; no. 13, DHEW publication -- no. (NIH) 77-813.
    The Physical Object
    Paginationix, 47, [37] p. :
    Number of Pages47
    ID Numbers
    Open LibraryOL15216437M

      In the present work the possible toxicity and teratogenicity of methylene chloride, 1,1,1-trichloroethane, 1,1,2-trichloroethane, trichloroethylene, tetrachloroethylene and toluene was studied with chick embryos. The chemical formulas of the tested compounds are shown in Fig. 1. NTP. TR Tetrachloroethylene (). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed

    Search for books, ebooks, and physical Bioassay of trisodium ethylenediaminetetraacetate trihydrate for possible carcinogenicity Published: () Bioassay of diazinon for possible carcinogenicity Published: () Bioassay of piperonyl sulfoxide for possible carcinogenicity Published: (). Tetrachloroethylene, also known under the systematic name tetrachloroethene, or perchloroethylene, and many other names (and abbreviations such as "perc" or "PERC", and "PCE"), is a chlorocarbon with the formula Cl 2 C=CCl is a colorless liquid widely used for dry cleaning of fabrics, hence it is sometimes called "dry-cleaning fluid".It has a sweet odor detectable by most people at a.

    64 synonyms of book from the Merriam-Webster Thesaurus, plus related words, definitions, and antonyms. Find another word for book. Book: a set of printed sheets of paper bound together between covers and forming a work of fiction or nonfiction. Get this from a library! Bioassay of hexachloroethane for possible carcinogenicity.. [National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.].


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Bioassay of tetrachloroethylene for possible carcinogenicity by National Institute of Health (U.S.). Carcinogen Bioassay and Program Resources Branch. Download PDF EPUB FB2

Additional Physical Format: Print version: Hazleton Laboratories America. Bioassay of tetrachloroethylene for possible carcinogenicity (OCoLC) The NTP cancer-bioassay did not provide evidence of hyaline droplets in rats exposed to carcinogenic doses of tetrachloroethylene for up to 2 years.

However, the NTP protocol at that time was not designed specifically to detect hyaline droplets or accumulation of α2u-globulin in the kidney (NTP, ). Books to Borrow. Top American Libraries Canadian Libraries Universal Library Community Texts Project Gutenberg Biodiversity Heritage Library Children's Library.

Open Library. Featured movies All video latest This Just In Prelinger Archives Democracy Now. Occupy Wall Street TV NSA Clip Library. Tetrachloroethylene: Target Organs and Levels of Evidence for TR Bioassay of Tetrachloroethylene for Possible Carcinogenicity (CASRN ) Chemical (Study Title).

Long-Term Carcinogenicity. 2-Year (Gavage) (CA) Completed. TR (NIH Number: ) (Peer Review Approval 09/26/A) Bioassay of Tetrachloroethylene for Possible Carcinogenicity (CASRN ) Rats: Osborne Mendel; Mice: B6C3F1; Carcinogenesis Results.

Male Rats Inadequate Study ; Female Rats Inadequate Study. NCI () National Cancer Institute. Bioassay of tetrachloroethylene for possible carcinogenicity. Publication no. NIH 77– U.S. Department of Health, Education and Welfare (DHEW), Public Health Service (PHS), National Institutes of Health, National Cancer Institute.

NTISb PB NTIS, Springfield, VA. Google Scholar. Tetrachloroethylene is a nonflammable colorless liquid with a sharp sweet odor; the odor threshold is 1 ppm.

(1) The chemical formula for tetrachloroethylene is C 2 Cl 4, and the molecular weight is g/mol. (1) The vapor pressure for tetrachloroethylene is mm Hg at 25 °C, and it.

Tetrachloroethylene (Cl₂C=CCl₂) is a colorless liquid with a mild, chloroform-like odor. Exposure to tetrachloroethylene may cause irritation eyes, skin, nose, throat, and respiratory system. It may also cause liver damage and is a potential occupational carcinogen.

Workers may be harmed from exposure to tetrachloroethylene. The NTP Peer Review Panel concluded that there was “clear evidence of carcinogenicity of tetrachloroethylene” (perchloroethylene) in male rats and in male and female mice, and “some evidence” in female rats (Ex.

Appendix 4; Ex.p. 11). SUMMARY The carcinogenesis bioassay of technical grade 1,1,1-Trichloroethane was. conducted using Osborne-Mendel rats and B6C3F1 mice. 1,1,1-Trichloroethane was. administered orally by gavage in corn oil to 50 animals of each sex and. species at. Get this from a library.

Bioassay of tetrachloroethylene for possible carcinogenicity. [National Cancer Institute (U.S.). Carcinogen Bioassay and Program Resources Branch.].

Series No. 13 1 9 7 7 BIOASSAY OF TETRACHLOROETHYLENE FOR POSSIBLE CARCINOGENICITY CAS REPORT ON THE BIOASSAY OF TETRACHLOROETHYLENE FOR POSSIBLE CARCINOGENICITY 3abs Abstract for TR Bioassay of Tetrachloroethylene for Possible Carcinogenicity CASRN: Chemical Formula: C2Cl4 Molecular Weight:.

Download. The majority of NCBI data are available for downloading, either directly from the NCBI FTP site or by using software tools to download custom datasets. Tetrachloroethylene (Perchloroethylene); CASRN carcinogenicity, a summary of that evaluation will be contained in Section II of this file.

The RfD of mg/kg-day replaces the previous RfD of mg/kg-day entered on the IRIS database on 03/01/ The previous RfD was based on a NOAEL of 14 mg/kg-day.

Bioassay of tetrachloroethylene for possible carcinogenicity, Bethesda, Maryland: National Cancer Institute, (HEW publication no. (NIH) ). National Institute for Occupational Safety and Health. Tetrachloroethylene (perchloroethylene).

Cincinnati, Ohio: National Institute for Occupational Safety and Health, Janu Carcinogenesis bioassay of trichloroethylene: CAS No. by United States. National Cancer Institute. Carcinogen Bioassay and Program Resources Branch; U.S. Dept.

of Health, Education, and Welfare, Public Health Service. National Institutes of Health. The bioassay of U.S.P. -grade tetrachloroethylene for possible carcinogenicity was conducted using Osborne-Mendel rats and B6C3F1 mice.

Tetrachloroethylene in corn oil was administered by gavage at either of two dosages to groups of 50 male and 50 female animals of each species, 5 days a week, over a period of 78 weeks followed by an.

Bioassay of 1,1,2,2-tetrachloroethane for possible carcinogenicity. (Book, ) [] Get this from a library. Bioassay of 1,1,2,2-tetrachloroethane for possible carcinogenicity.

The bioassay of U.S.P.-grade tetrachloroethylene for possible carcinogenicity was conducted using Osborne-Mendel rats and B6C3F1 mice. Tetrachloroethylene in corn oil was administered by gavage at either of two dosages to groups of 50 male and 50 female animals of each species, 5 days a week, over a period of 78 weeks followed by an observation period of 32 weeks for.

Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M. The U.S.

EPA’s analysis found that a wide range of possible contributions of TCA to PCE carcinogenicity, from as little as 12% to as much as %, is consistent with the available data (U.S.

EPA b). A more precise quantitative estimate of the relative contribution of TCA to PCE-induced liver tumors requires an appropriately designed study.This criterion is based on carcinogenicity of risk. Alternate risk levels may be obtained by moving the decimal point (e.g., for a risk level ofmove the decimal point in the recommended criterion one place to the right).

Benzo(a)anthracene (P) This criterion is based on carcinogenicity of risk.Addendum to the Health Assessment Document for Tetrachloroethylene (Perchloroethylene): Updated Carcinogenicity Assessment for Tetrachloroethylene (Perchloroethylene, PERC, PCE).

EPA///FA. External Review Draft. (Available from National Technical Information Service, Springfield, Va., as publication no. PB).